This should be left in place for 30 seconds. Tell your doctor if you are pregnant or plan on getting pregnant. For patients in the study group, PVIP gargle and nasal sprays will be applied preoperatively or shortly after admission and enrollment in the study for the non-operative group. Povidone-iodine (PVP-I) is a broad-spectrum antiseptic with activity against bacteria, fungi, and viruses. doi: 10.1002/14651858.CD013626.pub2. Then, the participant will gargle the solution for 30 seconds and not have anything to eat or drink by mouth for 30 minutes. Listing a study does not mean it has been evaluated by the U.S. Federal Government.ClinicalTrials.gov Identifier: NCT04364802,Interventional If Betadine (povidone-iodine (topical products)) is swallowed, call a doctor or poison control center right away. Additionally, they will receive povidone-iodine nasal spray and gargle (10% diluted 1:30) to use at the beginning of their shift, in the middle, and at the end of their shift.Inpatients who have a 7+ day hospitalization or who are set to undergo a significant surgical procedure will receive standard care and a pre- and post-study COVID-19 test.Inpatients who have a 7+ day hospitalization or who are set to undergo a significant surgical procedure will receive standard care and a pre- and post-study COVID-19 test. Additionally, they will receive povidone-iodine nasal spray and gargle shortly after admission or preoperatively.Percent of healthcare workers that become positive for COVID-19 during the study.Percent of patients that become positive for COVID-19 during the study.Patients will rate the ease of use for PVP-I treatment on a scale from 1-5 after the initial use. Additionally, they will receive PVP-I spray and gargle.Healthcare workers will receive standard PPE and a pre- and post-study nasal swab COVID19 test. Lower scores indicate increased ease of use (1="easy") while higher scores indicate increased difficulty (5="impossible").Patients will rate the comfort of PVP-I treatment on a scale from 1-5 after the initial use. Betadine First Aid Solution (10% Povidone Iodine) has been trusted by healthcare professionals to help prevent infections for over 50 years. It has been previously used in both intranasal preparations against Methicillin Resistant Staphylococcus Aureus (MRSA) as well as oral preparations in in-vitro studies of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV), influenza H1N1, and rotavirus with good efficacy. Kids wear their cuts and scrapes with pride. For adequate coverage, the participant should be able to taste the iodine or see it in the back of the throat. The virus is thought to spread via respiratory droplets with the potential for transmission via inhalation of droplets, contact to the nose and mouth with infected materials, and airborne transmission.
The patients will then be retested in 2 weeks or as directed by the presentation of symptoms concerning for infection with SARS-CoV-2.COVID-19 is an emerging, rapidly evolving situation.Get the latest research information from NIH:You have reached the maximum number of saved studies (100).Please remove one or more studies before adding more.Information provided by (Responsible Party):Povidone-iodine (PVP-I) is a broad-spectrum antiseptic with activity against bacteria, fungi, and viruses. And when you treat their minor wounds with Betadine, you can feel assured by the signature golden-brown spot that Betadine is working to help prevent infection. At completion of the study, they will be asked to turn in their calendar card to assess how many applications they were able to complete.Given the high rate of asymptomatic carriers, a second arm will also be planned for patients who have a 7+ day hospitalization or who are set to undergo a significant surgical procedure. Review.U.S.
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